Hyperthermia Abstract Gene List(volchange1_pval<0.005)

Probe	Symbol	Description	Chromosome	Chromosome Location	GenBank	Gene	UniGene	PubMed	Gene Ontology	Pathway	pval	CORRELATION
Cfa.114.1.S1_at	TERT	telomerase reverse transcriptase	34	14294247	AF380351	403412	Cfa.114	7	DNA binding telomerase activity telomeric template RNA reverse transcriptase activity RNA binding binding RNA-dependent DNA replication intracellular membrane-bounded organelle nuclear part
Cfa.11644.1.A1_at					CO595457							-0.647
Cfa.12222.1.A1_at	NKG7	natural killer cell group 7 sequence	1		CO662639	476398	Cfa.12222		membrane			-0.645
Cfa.1240.1.A1_at					CO593331
Cfa.12805.1.A1_at					CO715914
Cfa.12841.1.S1_at	SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	24		DN745252	485837	Cfa.30579		plasma membrane protein domain specific binding skeletal muscle fiber development
Cfa.12849.1.A1_at					CO715121
Cfa.13943.2.A1_a_at					CO685057							-0.628
Cfa.14725.1.A1_at	PPP1R12B	protein phosphatase 1, regulatory (inhibitor) subunit 12B	7		CO669703	490230	Cfa.34670		protein binding organ morphogenesis cellular component organization cellular metabolic process intracellular part regulation of cellular process	Vascular smooth muscle contraction
Cfa.14828.1.A1_at					CO665996							-0.6
Cfa.15731.1.S1_at	RBM39	RNA binding motif protein 39	24		CF406273	477216	Cfa.15731		nucleotide binding alternative nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome larval development transcription cofactor activity RNA binding nucleus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process mRNA processing multicellular organismal development RNA splicing embryonic development multicellular organismal aging regulation of growth rate intracellular membrane-bounded organelle organ development tissue morphogenesis genitalia development regulation of biological process
Cfa.16590.1.S1_s_at	CXCL10	chemokine (C-X-C motif) ligand 10	32	-3562713	NM_001010949	478432	Cfa.16590		angiogenesis response to molecule of bacterial origin positive regulation of leukocyte migration immune response cell communication chemokine activity cell proliferation response to heat response to mechanical stimulus response to ionizing radiation protein transport leukocyte chemotaxis response to vitamin extracellular region part	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Cytosolic DNA-sensing pathway		-0.591
Cfa.17741.1.S1_s_at	ACTN3	actinin, alpha 3	18		DN414596	483707	Cfa.21263		muscle system process transcription coactivator activity actin binding calcium ion binding cell-substrate adherens junction cellular amino acid metabolic process apoptosis response to stress actin filament organization adult locomotory behavior embryonic development thyroid hormone receptor activator activity pyridoxal phosphate binding dendrite secretory granule membrane I band actin filament bundle macromolecular complex regulation of growth rate identical protein binding positive regulation of endocytosis negative regulation of cellular process	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)		-0.639
Cfa.17757.1.S1_at	TRIM72	tripartite motif-containing 72	6		DN424689	489927	Cfa.17757		system process protein binding phospholipid binding plasma membrane plasma membrane organization zinc ion binding vesicle membrane vesicle-mediated transport intracellular organelle organ development protein oligomerization
Cfa.18611.1.S1_at					BM539290
Cfa.18904.1.S1_s_at	IFI44	interferon-induced protein 44	6		DN268079	490198	Cfa.36757					-0.617
Cfa.19122.1.S1_at	LOC612325	hypothetical protein LOC612325	4		CO702387	612325	Cfa.19122
Cfa.19440.1.S1_s_at	CCDC158	coiled-coil domain containing 158	32		CF410419	478436	Cfa.33274		morphogenesis of an epithelium system process protein binding transport cellular component movement organelle organization nervous system development anatomical structure morphogenesis embryonic development ending in birth or egg hatching endomembrane system striated muscle tissue development actin cytoskeleton membrane cellular component assembly actin filament-based process cell projection organization actin cytoskeleton organization multicellular organismal process developmental process cellular component morphogenesis cell projection intracellular membrane-bounded organelle protein complex cytoskeletal part cytoplasmic part intracellular transport cell development organ development embryonic morphogenesis regulation of biological process establishment of localization in cell
Cfa.20819.1.S1_at	TAF7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	2		CX009596	487180	Cfa.20819		reproduction mitotic cell cycle M phase transcription factor TFIID complex cytoskeleton transcription initiation from RNA polymerase II promoter general RNA polymerase II transcription factor activity enzyme binding steroid hormone receptor signaling pathway regulation of cellular metabolic process multicellular organismal process developmental process regulation of organelle organization locomotion chromosomal part cytoplasmic part positive regulation of biological process localization	Basal transcription factors
Cfa.21143.1.S1_s_at	LOC479837	similar to limkain b1 isoform 1	6		DN420585	479837	Cfa.19892		nucleotide binding nucleic acid binding			-0.696
Cfa.21279.1.S1_s_at	CASQ2	calsequestrin 2 (cardiac muscle)	17		DN368887	483134	Cfa.12728		calcium ion binding endoplasmic reticulum lumen muscle contraction striated muscle tissue development terminal cisterna response to muscle inactivity involved in regulation of muscle adaptation sarcomere regulation of homeostatic process response to chemical stimulus sarcolemma vesicular fraction membrane part			-0.61
Cfa.2207.1.A1_at					BU751706
Cfa.2300.1.A1_at					CF406346
Cfa.2507.1.S1_at					CF408337
Cfa.273.4.A1_s_at	NDUFC2	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa	21		CO704352	476794	Cfa.40189		mitochondrial inner membrane mitochondrial electron transport, NADH to ubiquinone NADH dehydrogenase (ubiquinone) activity intracellular membrane-bounded organelle	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
Cfa.2955.3.A1_x_at	LOC491504	similar to Myomesin 2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein)	16		CF413359	491504	Cfa.40114		muscle system process catalytic activity structural molecule activity protein binding organelle organization anatomical structure morphogenesis striated muscle tissue development A band intracellular non-membrane-bounded organelle cell development			-0.634
Cfa.3173.2.A1_a_at					CO698010				binding acute-phase response sterol metabolic process extracellular region part			-0.609
Cfa.3293.1.A1_at	HMGCR	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	3		AJ536931	479182	Cfa.3293		hydroxymethylglutaryl-CoA reductase (NADPH) activity endoplasmic reticulum membrane negative regulation of protein kinase activity steroid biosynthetic process triterpenoid metabolic process transport endocytosis learning cholesterol metabolic process ergosterol metabolic process germ cell migration embryonic development organ morphogenesis lipid localization endomembrane system coenzyme A metabolic process integral to membrane terpenoid biosynthetic process sterol biosynthetic process reproductive process organelle membrane mitochondrial lumen macromolecule localization growth regulation of growth locomotion response to chemical stimulus microbody vesicular fraction identical protein binding organ development NADP or NADPH binding coenzyme binding localization establishment of localization oxidation reduction regulation of primary metabolic process	Terpenoid backbone biosynthesis Metabolic pathways
Cfa.5663.1.A1_at					CO617712
Cfa.6195.1.A1_x_at	RPS11	Ribosomal protein S11	1		CO658740	403684	Cfa.39143	1	larval development structural constituent of ribosome translation mitotic spindle organization embryonic development multicellular organismal aging lipid localization small ribosomal subunit molting cycle, protein-based cuticle external encapsulating structure maturation of SSU-rRNA preribosome ribosomal subunit assembly intracellular membrane-bounded organelle	Ribosome
Cfa.6214.1.A1_at					CO663079							-0.694
Cfa.6765.1.A1_at	EEFSEC	eukaryotic elongation factor, selenocysteine-tRNA-specific	20		CO706061	476514	Cfa.6765		RNA binding GTPase activity GTP binding translational readthrough intracellular membrane-bounded organelle cytoplasmic part
Cfa.7289.1.A1_a_at	SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	8		CO609303	480424	Cfa.7289		serine-type endopeptidase inhibitor activity binding response to stress response to external stimulus response to inorganic substance regulation of proteolysis cell part male gamete generation response to steroid hormone stimulus	Complement and coagulation cascades
Cfa.7327.2.A1_a_at					CO608058							-0.72
Cfa.8318.1.A1_at					CO602171
Cfa.86.1.A1_at	FGFR2IIIC	FGF receptor 2IIIc			AJ439897	403569	Cfa.86		lytic vacuole cell morphogenesis involved in differentiation ossification metanephros development endodermal cell fate specification positive regulation of protein amino acid phosphorylation glandular epithelial cell differentiation fibroblast growth factor receptor activity ATP binding apoptosis smoothened signaling pathway brain development salivary gland morphogenesis positive regulation of cell proliferation negative regulation of cell proliferation fibroblast growth factor receptor signaling pathway specification of organ identity gene expression striated muscle tissue development integral to membrane morphogenesis of embryonic epithelium protein ubiquitination fibroblast growth factor binding developmental maturation cell projection organization respiratory tube development fin morphogenesis limb morphogenesis multicellular organism growth inner ear morphogenesis mechanoreceptor differentiation homeostatic process chordate embryonic development positive regulation of MAPKKK cascade plasma membrane part blood vessel morphogenesis digestive tract morphogenesis lateral line development branching involved in prostate gland morphogenesis branch elongation of an epithelium mesenchymal-epithelial cell signaling regulation of morphogenesis of a branching structure			-0.609
Cfa.9405.1.A1_at					CO687747
CfaAffx.10877.1.S1_at	DPYSL3	dihydropyrimidinase-like 3	2		PMRNA10777	487204	Cfa.42816		cell fraction pyrimidine binding cytochrome-c oxidase activity mitochondrion pyrimidine base catabolic process transport cellular component movement hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides protein domain specific binding cell projection organization polysaccharide binding site of polarized growth carboxylic acid binding macromolecular complex neuron projection transition metal ion binding cell development system development protein homooligomerization			-0.617
CfaAffx.11027.1.S1_at	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	2		PMRNA10927	487207	Cfa.42815		serine-type endopeptidase activity binding proteolysis apoptosis cell part positive regulation of biological process regulation of cellular process	Neuroactive ligand-receptor interaction		-0.739
CfaAffx.11111.1.S1_s_at	OVCH2	ovochymase 2	21		PMRNA11011	485368			serine-type endopeptidase activity proteolysis response to wounding membrane multicellular organismal process biological regulation
CfaAffx.13041.1.S1_s_at	FMN1	formin 1	30		PMRNA12941	478248	Cfa.39215		actin binding plasma membrane actin filament organization anatomical structure morphogenesis actin cytoskeleton reproductive process cellular component assembly organ development regulation of biological process localization
CfaAffx.13763.1.S1_at	ZCCHC9	zinc finger, CCHC domain containing 9	3		PMRNA13663	479161	Cfa.352		nucleic acid binding zinc ion binding cellular process intracellular part regulation of biological process			-0.67
CfaAffx.14100.1.S1_at	ARFGAP2	ADP-ribosylation factor GTPase activating protein 2	18		PMRNA14000	483627	Cfa.17688		Golgi-associated vesicle transport multicellular organismal development ARF GTPase activator activity zinc ion binding embryonic development cellular process protein transport vesicle coat regulation of ARF GTPase activity intracellular membrane-bounded organelle cytoplasmic part Golgi transport vesicle coating gametophyte development	Endocytosis
CfaAffx.15788.1.S1_at	IQCF5	IQ motif containing F5	20		PMRNA15688	484749	Cfa.20965
CfaAffx.1705.1.S1_at	LOC481471	similar to interferon gamma inducible protein 47	11		PMRNA1605	481471	Cfa.42160		GTP binding response to stress membrane hydrolase activity, acting on acid anhydrides intracellular membrane-bounded organelle			-0.587
CfaAffx.17556.1.S1_at	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3	34		PMRNA17456	488085			potassium ion transport calcium-activated potassium channel activity integral to membrane	Vascular smooth muscle contraction
CfaAffx.18789.1.S1_at	LOC608121	similar to piggyBac transposable element derived 5	4		PMRNA18689	608121	Cfa.43782
CfaAffx.18997.1.S1_s_at	GAS2L1	growth arrest-specific 2 like 1	26		PMRNA18897	486342	Cfa.41435		binding cell cycle arrest anatomical structure morphogenesis cellular component organization intracellular organelle organ development
CfaAffx.19561.1.S1_s_at	cOR51H4	cOR51H4 olfactory receptor family 51 subfamily H-like	21		PMRNA19461	491661		1	olfactory receptor activity G-protein coupled receptor protein signaling pathway integral to membrane	Olfactory transduction
CfaAffx.19720.1.S1_at	NKX1-2	NK1 homeobox 2	28		PMRNA19620	486929			regionalization heart morphogenesis system process transcription factor activity nucleus generation of precursor metabolites and energy regulation of transcription, DNA-dependent imaginal disc development forebrain development cardiac cell differentiation muscle cell differentiation sequence-specific DNA binding positive regulation of biological process generation of neurons cardiac muscle tissue development
CfaAffx.20910.1.S1_s_at	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	X		PMRNA20810	480869	Cfa.5876		nucleotide binding nucleoside binding DNA-directed DNA polymerase activity nucleus replication fork DNA-dependent DNA replication DNA repair multicellular organismal development hydrolase activity protein complex structure-specific DNA binding protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication		-0.636
CfaAffx.21174.1.S1_at	USP28	ubiquitin specific peptidase 28	5		PMRNA21074	489400	Cfa.20714		ubiquitin thiolesterase activity ATP binding ubiquitin-dependent protein catabolic process cell part
CfaAffx.21200.1.S1_s_at	LOC612044	similar to solute carrier family 22 (organic anion transporter), member 20	18		PMRNA21100	612044			binding anion transmembrane transporter activity secondary active transmembrane transporter activity organic cation transport organic anion transport response to chemical stimulus plasma membrane part transmembrane transport
CfaAffx.22488.1.S1_at	PYGL	phosphorylase, glycogen, liver	8		PMRNA22388	403738	Cfa.33596		cell fraction phosphorylase activity endoplasmic reticulum glycogen metabolic process cellular metal ion homeostasis response to stress plastid response to abiotic stimulus embryonic development response to organic substance pyridoxal phosphate binding carbohydrate binding adenyl ribonucleotide binding macromolecular complex identical protein binding neuron projection ribose phosphate biosynthetic process cofactor binding cell division	Starch and sucrose metabolism Insulin signaling pathway
CfaAffx.24660.1.S1_at	IGFBP4	insulin-like growth factor binding protein 4	9		PMRNA24560	608158	Cfa.39661		regulation of cell growth insulin-like growth factor binding defense response signal transduction response to external stimulus cellular metabolic process primary metabolic process extracellular region part cell part organ development negative regulation of biological process response to steroid hormone stimulus
CfaAffx.25633.1.S1_s_at	NES	nestin	7		PMRNA25533	490410	Cfa.42432		structural molecule activity cellular process membrane intracellular organelle cytoplasmic part system development response to stimulus
CfaAffx.26145.1.S1_s_at	RAD23A	RAD23 homolog A (S. cerevisiae)	20		PMRNA26045	484922	Cfa.17794		reproduction damaged DNA binding protein binding nucleus cytoplasm DNA repair nucleotide-excision repair proteolysis protein catabolic process proteasomal ubiquitin-dependent protein catabolic process intracellular membrane-bounded organelle cellular macromolecule catabolic process cellular protein metabolic process cytoplasmic part male gamete generation	Nucleotide excision repair		-0.591
CfaAffx.26857.1.S1_at					PMRNA26757							-0.635
CfaAffx.27154.1.S1_at	BRIP1	BRCA1 interacting protein C-terminal helicase 1	9		PMRNA27054	491122			DNA binding ATP-dependent DNA helicase activity ATP binding DNA metabolic process response to DNA damage stimulus intracellular part			-0.597
CfaAffx.27631.1.S1_at					PMRNA27531				mitotic cell cycle conjugation compound eye photoreceptor fate commitment nematode larval development ATP binding extracellular region insoluble fraction microtubule organizing center nucleobase, nucleoside, nucleotide and nucleic acid metabolic process protein folding protein targeting nitrogen compound metabolic process nitric oxide biosynthetic process response to stress defense response response to osmotic stress telomere maintenance via telomerase cell communication signal transduction cell surface receptor linked signaling pathway gamete generation pole plasm RNA localization fungal-type cell wall response to heat response to abiotic stimulus embryonic development post-embryonic development response to organic substance response to inorganic substance multicellular organismal aging gene expression skeletal myofibril assembly membrane ATPase activity cyclic-nucleotide-mediated signaling sexual reproduction cell cycle process reproductive process regulation of cell morphogenesis endocytic vesicle enzyme regulator activity myofibril assembly intracellular receptor-mediated signaling pathway sorocarp development regulation of cellular metabolic process regulation of cellular biosynthetic process regulation of protein stability I band nuclear lumen small conjugating protein binding macromolecule localization cellular macromolecule biosynthetic process growth response to chemical stimulus regulation of circadian sleep/wake cycle identical protein binding intracellular membrane-bounded organelle cellular protein complex assembly cellular biosynthetic process symbiosis, encompassing mutualism through parasitism cytoplasmic part negative regulation of transcription by carbon catabolites cytotoxic T cell differentiation male gamete generation meristem development phyllome development regulation of developmental process unfolded protein binding regulation of cellular component organization regulation of nitrogen compound metabolic process regulation of multicellular organismal process regulation of macromolecule metabolic process regulation of primary metabolic process
CfaAffx.27858.1.S1_at	RASL10B	RAS-like, family 10, member B	9		PMRNA27758	491138			GTP binding intracellular small GTPase mediated signal transduction multicellular organismal development protein transport membrane
CfaAffx.27981.1.S1_s_at	PPARGC1B	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	4		PMRNA27881	489190	Cfa.36104		nucleotide binding nucleic acid binding protein binding positive regulation of cellular metabolic process response to corticosteroid stimulus intracellular part regulation of transcription
CfaAffx.28359.1.S1_s_at	WDR78	WD repeat domain 78	5		PMRNA28259	479538	Cfa.40467		cellular process microtubule cytoskeleton cytoskeletal part			-0.669
CfaAffx.29666.1.S1_at					PMRNA29566
CfaAffx.31229.1.S1_at	PDP2	pyruvate dehyrogenase phosphatase catalytic subunit 2	5		PMRNA31129	489771	Cfa.42558		protein serine/threonine phosphatase activity protein binding mitochondrial matrix protein amino acid dephosphorylation protein serine/threonine phosphatase complex response to carbohydrate stimulus positive regulation of molecular function metal ion binding			-0.602
CfaAffx.3153.1.S1_s_at	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	10		PMRNA3053	481271	Cfa.6221		MAPKKK cascade syncytium formation by plasma membrane fusion establishment of imaginal disc-derived wing hair orientation tissue homeostasis immune effector process regulation of immune system process GTP binding insoluble fraction regulation of DNA replication phagocytosis, engulfment chemotaxis defense response response to osmotic stress response to DNA damage stimulus microtubule-based process cell adhesion Ras protein signal transduction ovarian follicle cell migration initiation of dorsal closure axon guidance open tracheal system development salivary gland development regulation of actin polymerization or depolymerization cell proliferation regulation of lamellipodium assembly regulation of cell morphogenesis involved in differentiation endomembrane system protein transport nucleoside-triphosphatase activity pole plasm mRNA localization extrinsic to membrane kinase binding cerebral cortex cell migration substrate-independent telencephalic tangential interneuron migration actin filament polymerization endocytic vesicle sorocarp development cell leading edge positive regulation of kinase activity cell junction maintenance vulval development compound eye photoreceptor development hemocyte differentiation neuron projection plasma membrane part axon extension genitalia development neuromuscular process cell division response to other organism	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Pancreatic cancer Viral myocarditis		-0.597
CfaAffx.3347.1.S1_s_at	SLC24A2	solute carrier family 24 (sodium/potassium/calcium exchanger), member 2	11		PMRNA3247	481554	Cfa.22835		cation channel activity protein binding insoluble fraction cellular metal ion homeostasis learning or memory calcium:cation antiporter activity integral to membrane developmental process regulation of synaptic plasticity transmembrane transport divalent metal ion transport
CfaAffx.5829.1.S1_at	BMP10	bone morphogenetic protein 10	10		PMRNA5729	481408	Cfa.21136		ossification eye development urogenital system development formation of primary germ layer cell fate specification cell fate determination morphogenesis of a branching structure positive regulation of protein amino acid phosphorylation instar larval or pupal development reproductive developmental process cardiac muscle hypertrophy transmembrane receptor protein serine/threonine kinase signaling pathway central nervous system development open tracheal system development imaginal disc pattern formation growth factor activity positive regulation of cell proliferation post-embryonic development axis specification post-embryonic morphogenesis anterior/posterior pattern formation dorsal/ventral pattern formation regulation of gene expression regulation of anatomical structure morphogenesis myofibril assembly respiratory tube development appendage morphogenesis wing disc development tube morphogenesis growth regulation of growth negative regulation of cell differentiation oogenesis gland development response to stimulus positive regulation of developmental process regulation of multicellular organismal process cardiac muscle tissue morphogenesis cardiac muscle cell development trabecula formation epithelium development
CfaAffx.7111.1.S1_s_at	EEFSEC	eukaryotic elongation factor, selenocysteine-tRNA-specific	20		PMRNA7011	476514	Cfa.6765		RNA binding GTPase activity GTP binding translational readthrough intracellular membrane-bounded organelle cytoplasmic part
CfaAffx.9718.1.S1_at	APBB3	amyloid beta (A4) precursor protein-binding, family B, member 3	2		PMRNA9618	606955	Cfa.8054		protein binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transcription apoptosis cellular component movement response to DNA damage stimulus multicellular organismal development gene expression regulation of gene expression regulation of macromolecule biosynthetic process membrane cellular component organization regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle process multicellular organismal process cellular macromolecule biosynthetic process cell projection intracellular organelle negative regulation of biological process positive regulation of cellular process response to stimulus localization regulation of macromolecule metabolic process regulation of biological quality
CfaAffx.984.1.S1_at					PMRNA884							-0.649
RPTR-Cfa-AF403737-1_at					RPTR-CFA-AF403737-1							-0.614
RPTR-Cfa-M10961-4_at					RPTR-CFA-M10961-4

73 Genes