Hyperthermia Abstract Gene List(CHANGEADCPOST_pval<0.005)

Probe Symbol Description Chromosome Chromosome Location GenBank Gene UniGene PubMed Gene Ontology Pathway pval CORRELATION
Cfa.10574.1.A1_at         BU746954        
Cfa.10926.1.A1_at         CX008835         -0.688
Cfa.10989.1.S1_at         CO592060        
Cfa.11046.1.A1_s_at OMG oligodendrocyte myelin glycoprotein 9   CO589993 Cfa.11046  

binding

plasma membrane

cellular process

regulation of blood coagulation

intrinsic to membrane

 
Cfa.1206.1.A1_at GAD1 glutamate decarboxylase 1 (brain, 67kDa) 36 18369305 BQ752558 Cfa.45067 1

glutamate decarboxylase activity

protein binding

mitochondrion

glutamate decarboxylation to succinate

synaptogenesis

neuromuscular junction development

larval locomotory behavior

gamma-aminobutyric acid biosynthetic process

vesicle membrane

protein-pyridoxal-5-phosphate linkage

L-cysteine catabolic process to taurine

pyridoxal phosphate binding

axon

neurotransmitter biosynthetic process

synapse

neurotransmitter receptor metabolic process

synaptic transmission, GABAergic

Glutamate metabolism

Alanine and aspartate metabolism

beta-Alanine metabolism

Taurine and hypotaurine metabolism

Butanoate metabolism

Type I diabetes mellitus

Cfa.12104.1.A1_at RTDR1 rhabdoid tumor deletion region gene 1 26   CO604933 Cfa.12104  

protein binding

intracellular organelle

 
Cfa.12605.1.A1_at         CO719566        
Cfa.12929.1.A1_at         CO713314        
Cfa.13111.1.A1_at         CO718774         -0.724
Cfa.13192.1.S1_at MYLK myosin light chain kinase 33   CO705832 Cfa.13192  

calmodulin-dependent protein kinase activity

myosin light chain kinase activity

structural constituent of cytoskeleton

protein binding

protein amino acid phosphorylation

sarcomere

myofibril assembly

I band

intracellular organelle

intracellular non-membrane-bounded organelle

metal ion binding

Calcium signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Cfa.13469.1.A1_at         CO696044         -0.735
Cfa.13554.1.A1_at         CO693272        
Cfa.13578.1.A1_at         CO693377        
Cfa.13870.1.A1_at         CO687463        
Cfa.14004.1.A1_at SYNE1 spectrin repeat containing, nuclear envelope 1 1   CO686370 Cfa.35794  

actin binding

lamin binding

Golgi apparatus

nuclear organization and biogenesis

Golgi organization and biogenesis

integral to membrane

establishment of nucleus localization

muscle cell differentiation

postsynaptic membrane

  -0.712
Cfa.140.1.S1_s_at BRCA1 breast cancer 1, early onset 9 23278874 NM_001013416 Cfa.140 3

double-strand break repair via homologous recombination

condensed chromosome

damaged DNA binding

transcription coactivator activity

RNA binding

ubiquitin-protein ligase activity

centrosome

DNA replication

postreplication repair

regulation of transcription from RNA polymerase II promoter

regulation of transcription from RNA polymerase III promoter

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

chromosome segregation

zinc ion binding

gamma-tubulin ring complex

DNA damage response, signal transduction resulting in induction of apoptosis

dosage compensation, by inactivation of X chromosome

tubulin binding

negative regulation of transcription

enzyme binding

androgen receptor signaling pathway

positive regulation of protein ubiquitination

BRCA1-BARD1 complex

regulation of cell proliferation

chordate embryonic development

response to estrogen stimulus

negative regulation of fatty acid biosynthetic process

positive regulation of DNA repair

positive regulation of transcription, DNA-dependent

negative regulation of centriole replication

androgen receptor binding

Ubiquitin mediated proteolysis

-0.682
Cfa.14047.1.A1_s_at ELAC1 elaC homolog 1 (E. coli) 1   CO717858 Cfa.10700  

endonuclease activity

metabolic process

  -0.682
Cfa.14591.1.A1_at         CO672911        
Cfa.1473.1.A1_at         BU745067        
Cfa.15217.2.A1_at         BU747310        
Cfa.1528.1.A1_at         BU745602         -0.768
Cfa.15310.1.A1_at         CO690658        
Cfa.15466.1.S1_s_at SLU7 SLU7 splicing factor homolog (S. cerevisiae) 4   DN350550 Cfa.9139  

alternative nuclear mRNA splicing, via spliceosome

second spliceosomal transesterification activity

nuclear mRNA 3'-splice site recognition

nematode larval development

single-stranded RNA binding

spliceosome

mitotic spindle organization and biogenesis

zinc ion binding

positive regulation of cell proliferation

determination of adult life span

embryonic development ending in birth or egg hatching

nuclear speck

molting cycle, protein-based cuticle

small nuclear ribonucleoprotein complex

pre-mRNA 3'-splice site binding

growth

  -0.718
Cfa.1551.1.A1_at         BU745725         -0.688
Cfa.1573.2.S1_s_at NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 32   CO605456 Cfa.1573  

calcium activated cation channel activity

mitochondrion

integral to membrane

nucleoside-diphosphatase activity

ADP-sugar diphosphatase activity

metal ion transport

cation binding

ADP catabolic process

IDP catabolic process

metal ion binding

Purine metabolism

-0.706
Cfa.16226.1.S1_at PRKCD protein kinase C, delta 20 -39719805 NM_001008716 Cfa.16226  

regulation of cell growth

immunological synapse

calcium-dependent protein kinase C activity

calcium-independent protein kinase C activity

ATP binding

membrane fraction

nucleus

cytoplasm

induction of apoptosis

chemotaxis

intracellular signaling cascade

neurotransmitter secretion

chemosensory behavior

protein C-terminus binding

enzyme activator activity

embryonic development ending in birth or egg hatching

immunoglobulin mediated immune response

enzyme binding

diacylglycerol binding

interleukin-10 production

interleukin-12 production

positive regulation of locomotion

B cell proliferation

positive regulation of T cell proliferation

positive regulation of interleukin-2 biosynthetic process

metal ion binding

regulation of peptidyl-tyrosine phosphorylation

protein stabilization

positive regulation of NF-kappaB transcription factor activity

Tight junction

Cfa.171.2.S1_s_at TTN titin 36   AY134862 Cfa.1444 1

condensed nuclear chromosome

in utero embryonic development

heart morphogenesis

protein kinase activity

protein serine/threonine kinase activity

structural constituent of cytoskeleton

protein binding

calmodulin binding

ATP binding

muscle myosin complex

protein amino acid phosphorylation

muscle contraction

striated muscle contraction

mitosis

heart development

adult heart development

behavior

structural constituent of muscle

myosin binding

reproductive process

sarcomere

Z disc

myofibril assembly

M band

A band

I band

identical protein binding

forward locomotion

intracellular organelle

primary metabolic process

sarcomere organization

protein amino acid autophosphorylation

metal ion binding

response to stimulus

alpha-actinin binding

cardiac myofibril assembly

  -0.694
Cfa.1723.1.S1_s_at USP25 ubiquitin specific peptidase 25 31   DN425622 Cfa.1723  

proteasome complex

ubiquitin-specific protease activity

protein modification process

ubiquitin-dependent protein catabolic process

  -0.721
Cfa.17262.1.S1_s_at PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 1   DN393855 Cfa.19966  

nematode larval development

nucleus

locomotory behavior

embryonic development ending in birth or egg hatching

kinesin binding

growth

post-embryonic body morphogenesis

hermaphrodite genitalia development

biopolymer metabolic process

cellular metabolic process

primary metabolic process

  -0.688
Cfa.17438.1.S1_s_at TBL3 transducin (beta)-like 3 6   DN267536 Cfa.42496  

catalytic activity

receptor signaling protein activity

binding

rRNA processing

G-protein signaling, coupled to cGMP nucleotide second messenger

gamete generation

embryonic development ending in birth or egg hatching

embryonic development ending in seed dormancy

embryonic pattern specification

ribonucleoprotein complex

positive regulation of growth rate

nucleolar part

cell division

  -0.744
Cfa.17622.1.S1_at LOC610489 similar to Cytochrome P450 27, mitochondrial precursor (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) 37   DN338561 Cfa.17622  

binding

mitochondrial inner membrane

lipid metabolic process

calcium ion transport

steroid hydroxylase activity

25-hydroxycholecalciferol-24-hydroxylase activity

vitamin biosynthetic process

1-alpha,25-dihydroxyvitamin D3 (1,25-(OH)2D3) 24-hydroxylase activity

vitamin D metabolic process

Bile acid biosynthesis

PPAR signaling pathway

-0.679
Cfa.17725.1.S1_s_at DLAT dihydrolipoamide S-acetyltransferase 5   DN424711 Cfa.17725  

pyruvate dehydrogenase activity

dihydrolipoyllysine-residue acetyltransferase activity

protein binding

lipid particle

mitochondrial pyruvate dehydrogenase complex

acetyl-CoA biosynthetic process from pyruvate

gamete generation

embryonic development ending in birth or egg hatching

positive regulation of growth rate

macromolecule metabolic process

primary metabolic process

Glycolysis / Gluconeogenesis

Alanine and aspartate metabolism

Pyruvate metabolism

-0.685
Cfa.17828.1.S1_at TXNL4B thioredoxin-like 4B 5   DN383793 Cfa.17828  

spliceosome assembly

snRNP U5

cytoplasm

mitotic spindle organization and biogenesis

regulation of mitotic metaphase/anaphase transition

arsenate reductase (thioredoxin) activity

RNA splicing factor activity, transesterification mechanism

U4/U6 x U5 tri-snRNP complex

  -0.709
Cfa.17896.1.S1_s_at CDC5L CDC5 cell division cycle 5-like (S. pombe) 12   DN402187 Cfa.17896  

reproduction

nuclear mRNA splicing, via spliceosome

cytokinesis

gastrulation with mouth forming first

nematode larval development

transcription factor activity

protein binding

spliceosome

DNA repair

regulation of transcription, DNA-dependent

protein targeting

embryonic development ending in birth or egg hatching

defense response signaling pathway, resistance gene-dependent

defense response signaling pathway, resistance gene-independent

RNA splicing factor activity, transesterification mechanism

embryonic cleavage

defense response to bacterium

defense response to fungus

  -0.706
Cfa.17961.1.S1_s_at CUEDC2 CUE domain containing 2 28   CN004832 Cfa.17961  

protein binding

extracellular space

  0 -0.853
Cfa.17963.1.S1_s_at RAG1AP1 recombination activating gene 1 activating protein 1 7   DN373116 Cfa.7623  

nucleus

positive regulation of gene expression, epigenetic

  -0.679
Cfa.18141.1.S1_s_at SF3B2 splicing factor 3b, subunit 2, 145kDa 18   DN402118 Cfa.6665  

nuclear mRNA splicing, via spliceosome

nematode larval development

RNA binding

protein binding

spliceosome

snRNP U2

embryonic development ending in birth or egg hatching

growth

  -0.788
Cfa.18161.1.S1_s_at COL15A1 collagen, type XV, alpha 1 11   DN402208 Cfa.37504  

extracellular matrix structural constituent

binding

collagen type XV

basement membrane

extracellular space

cell adhesion

organ morphogenesis

extracellular matrix organization and biogenesis

regulation of cell proliferation

cell development

positive regulation of cellular process

localization

 
Cfa.18589.1.S1_s_at CUL4B cullin 4B X   DN343683 Cfa.41024  

G1/S transition of mitotic cell cycle

nuclear ubiquitin ligase complex

protein polyubiquitination

ubiquitin-protein ligase activity

protein binding

cell cycle arrest

negative regulation of cell proliferation

induction of apoptosis by intracellular signals

flower development

negative regulation of photomorphogenesis

leaf development

Nucleotide excision repair

Ubiquitin mediated proteolysis

-0.694
Cfa.1901.1.A1_at FBLIM1 filamin binding LIM protein 1 2   BU749270 Cfa.44722  

reproduction

receptor binding

interleukin-1 receptor binding

cytoskeleton

integral to plasma membrane

cell-cell adherens junction

focal adhesion

transport

cell adhesion

signal transduction

release of cytoplasmic sequestered NF-kappaB

cellular component organization and biogenesis

kinase binding

positive regulation of cell migration

identical protein binding

interleukin-1 receptor complex

positive regulation of cellular process

 
Cfa.19110.1.S1_s_at SEPT11 septin 11 32   CO716802 Cfa.36169  

cytokinesis

stress fiber

protein binding

GTP binding

protein heterooligomerization

  -0.691
Cfa.19323.1.S1_s_at FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 25   CN005818 Cfa.33595 2

ovarian follicle development

patterning of blood vessels

vasculogenesis

positive regulation of mesenchymal cell proliferation

vascular endothelial growth factor receptor activity

ATP binding

extracellular space

integral to plasma membrane

protein amino acid phosphorylation

female pregnancy

regulation of heart contraction

cell migration

growth factor binding

hemopoiesis

thyroid gland development

embryonic heart tube development

identical protein binding

surfactant homeostasis

cell fate commitment

endothelial cell differentiation

vascular endothelial growth factor receptor signaling pathway

alveolus development

cell maturation

positive regulation of epithelial cell proliferation

calcium ion homeostasis

Cytokine-cytokine receptor interaction

Focal adhesion

Cfa.19466.1.S1_s_at ZNF367 zinc finger protein 367 1   BM538807 Cfa.19466  

transcription factor activity

RNA polymerase II transcription factor activity

protein binding

nucleus

cytoplasm

regulation of transcription from RNA polymerase II promoter

cellular metal ion homeostasis

response to copper ion

  -0.709
Cfa.19520.1.S1_at STAT5A signal transducer and activator of transcription 5A 9   DN382105 Cfa.19520  

luteinization

natural killer cell differentiation

negative regulation of T-helper 2 type immune response

transcription factor activity

signal transducer activity

protein binding

nucleus

cytoplasm

immune response

JAK-STAT cascade

female pregnancy

lactation

regulation of steroid metabolic process

cytokine and chemokine mediated signaling pathway

sequestering of lipid

regulation of cell adhesion

regulation of epithelial cell differentiation

mammary gland development

positive regulation of multicellular organism growth

positive regulation of activated T cell proliferation

progesterone metabolic process

T cell homeostasis

sequence-specific DNA binding

positive regulation of interleukin-2 biosynthetic process

positive regulation of B cell differentiation

positive regulation of myeloid cell differentiation

negative regulation of erythrocyte differentiation

positive regulation of survival gene product expression

positive regulation of mitotic cell cycle

positive regulation of transcription from RNA polymerase II promoter

development of secondary female sexual characteristics

development of secondary male sexual characteristics

positive regulation of isotype switching to IgE isotypes

erythrocyte development

positive regulation of inflammatory response

Jak-STAT signaling pathway

Cfa.19766.1.A1_at         BU746958        
Cfa.20217.1.S1_at         BM539978         -0.715
Cfa.20269.1.A1_s_at ZFAND6 zinc finger, AN1-type domain 6 3   BU744645 Cfa.1005  

protein binding

signal transduction

  -0.718
Cfa.20881.1.S1_s_at SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 15   DN395838 Cfa.936  

condensed chromosome

morphogenesis of an epithelium

DNA binding

DNA helicase activity

ATP binding

transcription factor complex

nucleosome assembly

chromatin remodeling

transcription initiation

regulation of transcription from RNA polymerase II promoter

gamete generation

brain development

muscle development

DNA-dependent ATPase activity

chromatin accessibility complex

embryo sac development

embryonic development ending in birth or egg hatching

cell growth

general RNA polymerase II transcription factor activity

transcription activator activity

nucleosome positioning

NURF complex

ACF complex

RSF complex

brahma complex

ecdysone receptor-mediated signaling pathway

positive regulation of growth rate

hermaphrodite genitalia development

histone binding

nucleosome mobilization

positive regulation of gene-specific transcription

dendrite morphogenesis

Starch and sucrose metabolism

Folate biosynthesis

-0.691
Cfa.2349.1.S1_at         CF406776        
Cfa.2507.1.S1_at         CF408337        
Cfa.2677.1.S1_s_at GRIPAP1 GRIP1 associated protein 1 X   DN392993 Cfa.21311  

nucleotide binding

microtubule cytoskeleton organization and biogenesis

mitotic cell cycle

M phase

cell morphogenesis

motor activity

protein binding

endosome

spindle

cell cortex

microtubule-based process

cell adhesion

cytoskeletal protein binding

actin cytoskeleton

cell cycle process

cell projection

intracellular membrane-bounded organelle

protein complex

plasma membrane part

intracellular transport

cell development

organ development

regulation of cellular process

meiotic cell cycle

  -0.718
Cfa.3080.1.A1_at         CO590595        
Cfa.3480.1.A1_s_at GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 9 -28696380 NM_001003071 Cfa.3480 1

behavioral fear response

sprouting angiogenesis

GTPase activity

signal transducer activity

extracellular region

cytoplasm

heterotrimeric G-protein complex

receptor guanylyl cyclase signaling pathway

phototransduction

locomotory behavior

regulation of G-protein coupled receptor protein signaling pathway

cell proliferation

rhabdomere

vascular endothelial growth factor receptor signaling pathway

 
Cfa.3797.1.S1_s_at VASP vasodilator-stimulated phosphoprotein 1 -112941416 NM_001003256 Cfa.3797 1

neural tube closure

profilin binding

cytoplasm

focal adhesion

actin filament organization

cell surface receptor linked signal transduction

axon guidance

regulation of actin polymerization and/or depolymerization

organ morphogenesis

actin cytoskeleton

SH3 domain binding

lamellipodium

filopodium

intracellular transport

Focal adhesion

Leukocyte transendothelial migration

Cfa.4779.1.A1_at         CO710123        
Cfa.4807.1.A1_at         CO630443         -0.841
Cfa.4881.1.A1_at WIF1 WNT inhibitory factor 1 10   CO629970 Cfa.4881  

receptor binding

proteinaceous extracellular matrix

extracellular space

smoothened signaling pathway

multicellular organismal development

cellular component organization and biogenesis

Wnt-protein binding

protein metabolic process

cell differentiation

negative regulation of Wnt receptor signaling pathway

extracellular structure organization and biogenesis

extracellular matrix part

cell part

system development

protein stabilization

Wnt signaling pathway

-0.724
Cfa.5424.1.A1_s_at PIGU phosphatidylinositol glycan anchor biosynthesis, class U 24   CO702369 Cfa.5424  

GPI-anchor transamidase activity

plasma membrane

embryonic development ending in birth or egg hatching

attachment of GPI anchor to protein

GPI anchor binding

GPI-anchor transamidase complex

regulation of JAK-STAT cascade

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Glycan structures - biosynthesis 2

-0.794
Cfa.554.2.S1_at SDF4 stromal cell derived factor 4 5   DN443356 Cfa.554 1

binding

calcium ion binding

extracellular space

intracellular membrane-bounded organelle

cytoplasmic part

  -0.694
Cfa.6053.1.S1_at MCAM melanoma cell adhesion molecule 5   CX011117 Cfa.4686 1

blood vessel development

protein binding

extracellular space

heterophilic cell adhesion

axon guidance

cell surface

integral to membrane

cell soma

plasma membrane part

 
Cfa.6158.1.A1_at         CO700752        
Cfa.6362.1.A1_at APG-2 heat shock protein Apg-2 11 24320390 CO656108 Cfa.19900 2

ATP binding

nucleus

cytoplasm

response to unfolded protein

response to heat

chaperone cofactor-dependent protein folding

chaperone binding

Antigen processing and presentation

Cfa.6730.1.A1_at YPEL1 yippee-like 1 (Drosophila) 26   CO596293 Cfa.45345       -0.779
Cfa.7024.1.A1_at         CO603892        
Cfa.7738.1.A1_at         CO602867        
Cfa.8067.1.S1_at PBRM1 polybromo 1 20   CO625508 Cfa.34667  

nuclear chromosome

nucleic acid binding

chromatin binding

protein binding

chromatin remodeling

mitosis

post-embryonic development

biopolymer metabolic process

regulation of transcription

organ development

response to stimulus

  -0.706
Cfa.8253.1.A1_s_at CAGE1 cancer antigen 1 35   CO602927 Cfa.32409  

multicellular organismal development

cytoskeletal protein binding

intracellular membrane-bounded organelle

cytoplasmic part

cellular developmental process

  -0.688
Cfa.8418.1.A1_at         CO603688        
Cfa.8527.1.A1_at         CO598967         -0.7
Cfa.8579.1.A1_at         CO599049        
Cfa.9277.1.A1_at         CO588422        
Cfa.9352.1.A1_at JAKMIP2 janus kinase and microtubule interacting protein 2 2   CO594092 Cfa.9352  

peripheral to membrane of membrane fraction

RNA binding

cytoplasm

ribonucleoprotein complex

intracellular organelle

GABA receptor binding

  -0.679
Cfa.9401.1.A1_at         CO586113         -0.691
CfaAffx.10370.1.S1_at MAB21L1 mab-21-like 1 (C. elegans) 25   PMRNA10270 Cfa.41500  

nervous system development

positive regulation of cell proliferation

embryonic body morphogenesis

camera-type eye development

cell fate commitment

 
CfaAffx.1095.1.S1_s_at         PMRNA995        
CfaAffx.11027.1.S1_at GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2   PMRNA10927 Cfa.42815  

immunological synapse

complement factor D activity

granzyme A activity

granzyme B activity

extracellular space

nucleus

cytoplasm

proteolysis

cleavage of lamin

immune response

induction of apoptosis by granzyme

protein homodimerization activity

Neuroactive ligand-receptor interaction

-0.712
CfaAffx.11354.1.S1_at LOC610487 hypothetical protein LOC610487 26   PMRNA11254 Cfa.37822  

receptor activity

transporter activity

transport

membrane

  -0.679
CfaAffx.12134.1.S1_at LOC486249 similar to CG30100-PA 26   PMRNA12034    

aminoacyl-tRNA hydrolase activity

mitochondrion

  -0.703
CfaAffx.12276.1.S1_s_at LOC488888 hypothetical LOC488888 3   PMRNA12176 Cfa.21345       -0.694
CfaAffx.12327.1.S1_at LOC609897 hypothetical protein LOC609897 18   PMRNA12227 Cfa.43342       -0.715
CfaAffx.13398.1.S1_at SLC25A28 solute carrier family 25, member 28 28   PMRNA13298 Cfa.1019  

iron ion transmembrane transporter activity

binding

mitochondrial inner membrane

RNA splicing

embryonic development ending in birth or egg hatching

embryonic hemopoiesis

positive regulation of growth rate

erythrocyte maturation

mitochondrial iron ion transport

  -0.735
CfaAffx.13879.1.S1_s_at LOC478114 similar to CG14480-PA 2   PMRNA13779 Cfa.11613  

intracellular part

  -0.738
CfaAffx.1454.1.S1_at AVPR1A arginine vasopressin receptor 1A 10   PMRNA1354    

regulation of systemic arterial blood pressure by vasopressin

vasopressin receptor activity

protein kinase C binding

endosome

integral to plasma membrane

generation of precursor metabolites and energy

activation of phospholipase C activity

elevation of cytosolic calcium ion concentration

positive regulation of blood pressure

Calcium signaling pathway

Neuroactive ligand-receptor interaction

CfaAffx.14812.1.S1_s_at NISCH nischarin 20   PMRNA14712 Cfa.24687  

binding

 
CfaAffx.1499.1.S1_at WIF1 WNT inhibitory factor 1 10   PMRNA1399 Cfa.4881  

receptor binding

proteinaceous extracellular matrix

extracellular space

smoothened signaling pathway

multicellular organismal development

cellular component organization and biogenesis

Wnt-protein binding

protein metabolic process

cell differentiation

negative regulation of Wnt receptor signaling pathway

extracellular structure organization and biogenesis

extracellular matrix part

cell part

system development

protein stabilization

Wnt signaling pathway

-0.682
CfaAffx.1499.1.S1_s_at WIF1 WNT inhibitory factor 1 10   PMRNA1399 Cfa.4881  

receptor binding

proteinaceous extracellular matrix

extracellular space

smoothened signaling pathway

multicellular organismal development

cellular component organization and biogenesis

Wnt-protein binding

protein metabolic process

cell differentiation

negative regulation of Wnt receptor signaling pathway

extracellular structure organization and biogenesis

extracellular matrix part

cell part

system development

protein stabilization

Wnt signaling pathway

-0.691
CfaAffx.15149.1.S1_s_at KCNS1 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 24   PMRNA15049    

delayed rectifier potassium channel activity

protein binding

potassium ion transport

regulation of smooth muscle contraction

voltage-gated potassium channel complex

potassium channel regulator activity

 
CfaAffx.15313.1.S1_at ELOVL2 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 35   PMRNA15213 Cfa.10678  

microsome

integral to plasma membrane

G-protein coupled photoreceptor activity

fatty acid elongase activity

fatty acid elongation, unsaturated fatty acid

long-chain fatty acid biosynthetic process

very-long-chain fatty acid biosynthetic process

Biosynthesis of unsaturated fatty acids

CfaAffx.1547.1.S1_at RASGEF1C RasGEF domain family, member 1C 11   PMRNA1447 Cfa.42162  

Ras guanyl-nucleotide exchange factor activity

DNA metabolic process

regulation of cell shape

mushroom body development

hydrolase activity

 
CfaAffx.15859.1.S1_at NDN necdin homolog (mouse) 3   PMRNA15759 Cfa.42757  

regulation of cell growth

neuron migration

nucleus

centrosome

integral to plasma membrane

regulation of transcription, DNA-dependent

cellular calcium ion homeostasis

homophilic cell adhesion

axonal fasciculation

central nervous system development

embryo implantation

respiratory gaseous exchange

glial cell migration

sensory perception of pain

gamma-tubulin binding

protein complex

nerve growth factor receptor signaling pathway

axon extension involved in development

negative regulation of epithelial cell proliferation

  -0.721
CfaAffx.16270.1.S1_at ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 34   PMRNA16170 Cfa.41196  

metalloendopeptidase activity

binding

proteolysis

gene expression

extracellular matrix

extracellular region part

organ development

 
CfaAffx.16484.1.S1_s_at RBBP4 retinoblastoma binding protein 4 2   PMRNA16384 Cfa.17920  

negative regulation of transcription from RNA polymerase II promoter

cytokinesis

nematode larval development

chromatin binding

polytene chromosome

DNA repair

DNA replication-dependent nucleosome assembly

chromatin silencing

eggshell chorion gene amplification

muscle development

DNA-dependent ATPase activity

negative regulation of cell proliferation

embryonic development ending in birth or egg hatching

embryonic development ending in seed dormancy

regulation of flower development

trichome differentiation

seed coat development

transcription repressor activity

histone methylation

histone acetylation

NuRD complex

nucleosome positioning

NURF complex

ACF complex

Myb complex

histone acetyltransferase binding

ESC/E(Z) complex

hermaphrodite genitalia development

histone binding

nucleosome mobilization

histone deacetylase binding

histone lysine N-methyltransferase activity (H3-K9 specific)

histone lysine N-methyltransferase activity (H3-K27 specific)

embryonic digestive tract morphogenesis

dendrite morphogenesis

  -0.759
CfaAffx.16661.1.S1_s_at SLC38A11 solute carrier family 38, member 11 36   PMRNA16561    

amine transmembrane transporter activity

amino acid transport

membrane

 
CfaAffx.1703.1.S1_x_at SON SON DNA binding protein 31   PMRNA1603 Cfa.34162  

nuclear mRNA splicing, via spliceosome

larval development

DNA binding

RNA binding

double-stranded RNA binding

catalytic activity

adenosine deaminase activity

protein binding

proteinaceous extracellular matrix

nucleus

spliceosome

cytoplasm

mRNA processing

anti-apoptosis

multicellular organismal development

germ cell development

cellular component organization and biogenesis

base conversion or substitution editing

macromolecule metabolic process

intracellular organelle

cellular metabolic process

primary metabolic process

extracellular matrix part

intracellular part

membrane part

nuclear part

system development

  -0.735
CfaAffx.17399.1.S1_at CASP7 caspase 7, apoptosis-related cysteine peptidase 28   PMRNA17299    

B cell homeostasis

release of cytochrome c from mitochondria

cyclin-dependent protein kinase inhibitor activity

protein binding

endoplasmic reticulum membrane

DNA fragmentation during apoptosis

proteolysis

heart development

sensory perception of sound

induction of apoptosis via death domain receptors

induction of apoptosis by oxidative stress

response to UV

response to wounding

keratinocyte differentiation

nuclear fragmentation during apoptosis

caspase activity

negative regulation of B cell proliferation

mitochondrial membrane

response to chemical stimulus

T cell homeostasis

negative regulation of apoptosis

cell fate commitment

negative regulation of cyclin-dependent protein kinase activity

negative regulation of activated T cell proliferation

neuron apoptosis

Neurodegenerative Diseases

Apoptosis

Alzheimer's disease

Dentatorubropallidoluysian atrophy (DRPLA)

-0.709
CfaAffx.17520.1.S1_at LOC477825 similar to CTCL tumor antigen L14-2 28   PMRNA17420 Cfa.20081  

cellular process

cell part

  -0.744
CfaAffx.17729.1.S1_at CMKLR1 chemokine-like receptor 1 26   PMRNA17629    

activation of MAPK activity

skeletal development

anaphylatoxin receptor activity

chemokine receptor activity

N-formyl peptide receptor activity

endosome

integral to plasma membrane

cell motility

chemotaxis

inflammatory response

immune response

cell adhesion

G-protein signaling, coupled to cAMP nucleotide second messenger

nitric oxide mediated signal transduction

 
CfaAffx.18040.1.S1_at LOC610594 similar to olfactory receptor 414 38   PMRNA17940    

olfactory receptor activity

G-protein coupled receptor protein signaling pathway

sensory perception of smell

integral to membrane

Olfactory transduction

CfaAffx.18387.1.S1_at KLHL6 kelch-like 6 (Drosophila) 34   PMRNA18287    

protein binding

anterior/posterior pattern formation

cell surface

Wnt receptor signaling pathway

cell migration involved in gastrulation

intracellular organelle

  -0.724
CfaAffx.18434.1.S1_at         PMRNA18334        
CfaAffx.18511.1.S1_at VAX1 ventral anterior homeobox 1 28   PMRNA18411    

negative regulation of transcription from RNA polymerase II promoter

embryonic development via the syncytial blastoderm

neuron migration

transcription factor activity

specific RNA polymerase II transcription factor activity

protein binding

nucleus

immune response

blastoderm segmentation

specification of segmental identity, antennal segment

ectoderm development

negative regulation of neuroblast proliferation

axon guidance

ventral cord development

eye-antennal disc morphogenesis

heart development

visual perception

sensory perception of sound

post-embryonic development

dorsal/ventral axis specification

gastrulation involving germ band extension

B cell differentiation

forebrain development

midbrain development

chromatin DNA binding

spiracle morphogenesis, open tracheal system

brain segmentation

specification of segmental identity, mandibular segment

camera-type eye development

negative regulation of neuron apoptosis

cell fate commitment

embryonic eye morphogenesis

gut development

neuron fate commitment

regulation of cellular component organization and biogenesis

  -0.715
CfaAffx.19776.1.S1_at UBE4A ubiquitination factor E4A (UFD2 homolog, yeast) 5   PMRNA19676 Cfa.35978  

ubiquitin ligase complex

protein binding

ubiquitin-dependent protein catabolic process

Ubiquitin mediated proteolysis

-0.735
CfaAffx.19933.1.S1_s_at PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 27   PMRNA19833 Cfa.6170  

activation of MAPK activity

3',5'-cyclic-nucleotide phosphodiesterase activity

enzyme inhibitor activity

protein binding

visual perception

positive regulation of epidermal growth factor receptor signaling pathway

positive regulation of G-protein coupled receptor protein signaling pathway

Purine metabolism

CfaAffx.19956.1.S1_at         PMRNA19856        
CfaAffx.20612.1.S1_at LMX1A LIM homeobox transcription factor 1, alpha 38   PMRNA20512    

in utero embryonic development

neuron migration

transcription factor activity

protein binding

transcription factor complex

phagocytosis, engulfment

cell-cell signaling

axon guidance

muscle development

axis specification

dorsal/ventral pattern formation

transcription activator activity

cerebellum development

central nervous system neuron development

collagen fibril organization

embryonic limb morphogenesis

forebrain development

notochord development

midbrain-hindbrain boundary development

cell migration involved in gastrulation

camera-type eye development

sequence-specific DNA binding

negative regulation of neuron differentiation

positive regulation of transcription from RNA polymerase II promoter

anatomical structure formation

pronephros development

dendrite morphogenesis

 
CfaAffx.20764.1.S1_at WDR76 WD repeat domain 76 30   PMRNA20664         -0.688
CfaAffx.21111.1.S1_at LOC612129 hypothetical protein LOC612129 X   PMRNA21011    

metabolic process

oxidoreductase activity

 
CfaAffx.21170.1.S1_s_at DUOXA1 dual oxidase maturation factor 1 30   PMRNA21070 Cfa.40905  

protein binding

plasma membrane

asymmetric protein localization

olfactory learning

membrane part

basal part of cell

 
CfaAffx.2174.1.S1_at SAMD12 sterile alpha motif domain containing 12 13   PMRNA2074    

compound eye photoreceptor cell differentiation

cytoplasm

plasma membrane

epidermal growth factor receptor signaling pathway

compound eye cone cell differentiation

 
CfaAffx.21924.1.S1_at POU2AF1 POU class 2 associating factor 1 5   PMRNA21824 Cfa.42621  

DNA binding

transcription coactivator activity

transcription from RNA polymerase II promoter

humoral immune response

transferase activity

intracellular membrane-bounded organelle

  -0.685
CfaAffx.2200.1.S1_at GPR31 G protein-coupled receptor 31 1   PMRNA2100    

leukotriene receptor activity

GTP binding

integral to plasma membrane

ion transport

G-protein coupled receptor protein signaling pathway

peptide receptor activity, G-protein coupled

regulation of cAMP biosynthetic process

purinergic nucleotide receptor activity, G-protein coupled

5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding

5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding

5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding

 
CfaAffx.22305.1.S1_s_at DUSP3 dual specificity phosphatase 3 9   PMRNA22205 Cfa.6507  

protein tyrosine phosphatase activity

protein amino acid dephosphorylation

meiosis

spermatogenesis

protein tyrosine/serine/threonine phosphatase activity

MAPK signaling pathway

CfaAffx.22507.1.S1_s_at TNS1 tensin 1 37   PMRNA22407 Cfa.26399  

actin binding

intracellular

focal adhesion

cell-substrate junction assembly

positive regulation of cell proliferation

cell migration

alveolus development

 
CfaAffx.22641.1.S1_s_at PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 9   PMRNA22541 Cfa.5246  

protein binding

cytoplasm

cytoskeleton

multicellular organismal development

sensory perception

anatomical structure morphogenesis

membrane

cellular component organization and biogenesis

intracellular organelle part

localization

 
CfaAffx.23295.1.S1_s_at LDB2 LIM domain binding 2 3   PMRNA23195 Cfa.40785  

gastrulation with mouth forming second

DNA binding

transcription corepressor activity

nucleus

phagocytosis, engulfment

blastoderm segmentation

axon guidance

imaginal disc-derived wing morphogenesis

behavior

bristle morphogenesis

anterior/posterior axis specification

Wnt receptor signaling pathway

transcription activator activity

cerebellar Purkinje cell differentiation

LIM domain binding

protein homodimerization activity

protein complex

negative regulation of erythrocyte differentiation

negative regulation of transcription, DNA-dependent

positive regulation of transcription from RNA polymerase II promoter

 
CfaAffx.23948.1.S1_at SIX4 SIX homeobox 4 8   PMRNA23848 Cfa.42368  

ureteric bud development

transcription factor activity

protein binding

transcription factor complex

regulation of transcription, DNA-dependent

pattern specification process

adenohypophysis development

epithelial cell differentiation

thyroid gland development

inner ear morphogenesis

regulation of neuron differentiation

positive regulation of transcription

thymus development

embryonic skeletal morphogenesis

peripheral nervous system neuron development

myoblast migration

 
CfaAffx.23960.1.S1_s_at SGMS1 sphingomyelin synthase 1 26   PMRNA23860 Cfa.12025  

Golgi trans cisterna

protein binding

nucleus

endoplasmic reticulum

integral to plasma membrane

sphingomyelin biosynthetic process

inflammatory response

cell growth

integral to Golgi membrane

sphingomyelin synthase activity

negative regulation of apoptosis

ceramide cholinephosphotransferase activity

Sphingolipid metabolism

CfaAffx.23994.1.S1_s_at SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 3 72227604 PMRNA23894 Cfa.7132  

sugar:hydrogen symporter activity

fructose transmembrane transporter activity

glucose transmembrane transporter activity

integral to plasma membrane

carbohydrate metabolic process

fructose transport

intracellular part

glucose import

 
CfaAffx.24064.1.S1_at ACTA2 actin, alpha 2, smooth muscle, aorta 26   PMRNA23964 Cfa.45468 1

stress fiber

motor activity

structural constituent of cytoskeleton

ATP binding

soluble fraction

cytosol

striated muscle thin filament

actin filament

apoptosis

muscle contraction

regulation of heart contraction

structural constituent of muscle

myosin binding

muscle thin filament assembly

I band

embryonic heart tube development

ADP binding

cardiac myofibril assembly

cardiac muscle morphogenesis

 
CfaAffx.24213.1.S1_at SDCCAG8 serologically defined colon cancer antigen 8 7   PMRNA24113 Cfa.23121  

protein binding

centrosome

  -0.691
CfaAffx.24909.1.S1_s_at EMR3 egf-like module containing, mucin-like, hormone receptor-like 3 20 51022935 PMRNA24809 Cfa.24664 1

DNA binding

calcium ion binding

protein binding

integral to plasma membrane

cell adhesion

epidermal growth factor receptor signaling pathway

neuropeptide signaling pathway

external side of plasma membrane

epidermal growth factor-like module containing hormone receptor activity

response to stimulus

 
CfaAffx.2531.1.S1_s_at TRPC7 transient receptor potential cation channel, subfamily C, member 7 11   PMRNA2431   1

protein binding

integral to plasma membrane

calcium ion transport

elevation of cytosolic calcium ion concentration

phototransduction

store-operated calcium channel activity

cortical cytoskeleton

protein complex

membrane raft

  -0.724
CfaAffx.25633.1.S1_s_at NES nestin 7   PMRNA25533 Cfa.42432  

binding

cytoplasm

intermediate filament

central nervous system development

Cell Communication

CfaAffx.25687.1.S1_s_at PDZD11 PDZ domain containing 11 X   PMRNA25587 Cfa.40110  

cytosol

actin filament

cilium

protein complex assembly

protein targeting

exocytosis

establishment and/or maintenance of cell polarity

epidermal growth factor receptor signaling pathway

intracellular signaling cascade

neurotransmitter secretion

sensory perception of sound

protein C-terminus binding

asymmetric protein localization

basolateral plasma membrane

oviposition

synaptosome

water homeostasis

stereocilium

subapical complex

positive regulation of growth rate

positive regulation of vulval development

postsynaptic membrane

synaptic vesicle transport

inner ear receptor stereocilium organization and biogenesis

  -0.768
CfaAffx.2571.1.S1_at HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 11   PMRNA2471 Cfa.36439  

nuclear mRNA splicing, via spliceosome

single-stranded RNA binding

protein binding

nucleoplasm

spliceosome

cytoplasm

RNA export from nucleus

heterogeneous nuclear ribonucleoprotein complex

single-stranded telomeric DNA binding

nuclear import

  -0.7
CfaAffx.26437.1.S1_at         PMRNA26337         -0.797
CfaAffx.26684.1.S1_at         PMRNA26584        
CfaAffx.26718.1.S1_s_at NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 6   PMRNA26618 Cfa.6987  

double-strand break repair via homologous recombination

protein binding

nucleus

cytosol

meiotic gene conversion

meiotic recombination

intracellular signaling cascade

electron carrier activity

heme binding

ascospore formation

Smc5-Smc6 complex

replication fork protection

  -0.735
CfaAffx.27355.1.S1_at LYRM1 LYR motif containing 1 6   PMRNA27255 Cfa.45008  

mitochondrial inner membrane

oxidoreductase activity, acting on NADH or NADPH

  -0.732
CfaAffx.27435.1.S1_s_at UBL7 ubiquitin-like 7 (bone marrow stromal cell-derived) 30   PMRNA27335 Cfa.17975  

protein binding

protein targeting

membrane

  -0.815
CfaAffx.27491.1.S1_at LOC484960 similar to Complement C3 precursor 20   PMRNA27391 Cfa.46089  

positive regulation of type IIa hypersensitivity

receptor binding

signal transduction

cellular protein metabolic process

positive regulation of phagocytosis

 
CfaAffx.27809.1.S1_at IMPACT Impact homolog (mouse) 7   PMRNA27709    

regulation of cellular protein metabolic process

post-translational protein modification

intracellular part

  -0.765
CfaAffx.28169.1.S1_at LRRC48 leucine rich repeat containing 48 5   PMRNA28069 Cfa.11662  

cytoplasm

protein amino acid dephosphorylation

protein phosphatase type 1 regulator activity

  -0.682
CfaAffx.28417.1.S1_at ARHGAP28 Rho GTPase activating protein 28 7   PMRNA28317    

small GTPase regulator activity

GTPase activator activity

protein binding

cytoplasm

epidermal growth factor receptor signaling pathway

intracellular signaling cascade

dorsal closure

epithelial cell migration, open tracheal system

Malpighian tubule morphogenesis

midgut development

head involution

imaginal disc-derived wing vein morphogenesis

transferase activity

actin cytoskeleton organization and biogenesis

maintenance of epithelial integrity, open tracheal system

spiracle morphogenesis, open tracheal system

  -0.697
CfaAffx.28431.1.S1_s_at MYH11 myosin, heavy chain 11, smooth muscle 6   PMRNA28331 Cfa.39739  

microfilament motor activity

meiotic spindle organization and biogenesis

cytokinesis after mitosis

angiogenesis

in utero embryonic development

stress fiber

ruffle

establishment of planar polarity

neuron migration

establishment of T cell polarity

immunological synapse

plasma membrane repair

uropod

calmodulin binding

ATP binding

nucleus

spindle

contractile ring

cytosol

muscle myosin complex

cell-cell adherens junction

membrane protein ectodomain proteolysis

exocytosis

substrate-bound cell migration, cell extension

smooth muscle contraction

nuclear migration

meiotic metaphase I

integrin-mediated signaling pathway

ovarian follicle cell migration

dorsal closure, spreading of leading edge cells

axon guidance

salivary gland morphogenesis

Malpighian tubule morphogenesis

adult heart development

myoblast fusion

head involution

cell proliferation

integrin complex

structural constituent of muscle

regulation of cell shape

protein transport

muscle attachment

cell-cell adhesion

unconventional myosin complex

fourth ventricle development

lateral ventricle development

third ventricle development

cerebellar Purkinje cell layer development

Z disc

actin filament-based movement

platelet formation

monocyte differentiation

muscle thick filament assembly

axon

growth cone

smooth muscle contractile fiber

midbody

regulation of polarized epithelial cell differentiation

cortical cytoskeleton

actin-dependent ATPase activity

actin cytoskeleton reorganization

neuromuscular junction

myosin light chain binding

cleavage furrow

uropod organization and biogenesis

cuticle pattern formation

ecdysone-mediated induction of salivary gland cell autophagic cell death

imaginal disc-derived wing hair organization and biogenesis

protein homodimerization activity

cell soma

dendritic spine

protein anchor

ADP binding

blood vessel endothelial cell migration

apical cortex

establishment of neuroblast polarity

sarcomere organization

dorsal closure, leading edge cell differentiation

dorsal closure, amnioserosa morphology change

elastic fiber assembly

gut morphogenesis

cardiac muscle fiber development

neuromuscular process controlling balance

leukocyte migration

actin filament binding

establishment of meiotic spindle localization

cardiac myofibril assembly

ventricular cardiac muscle cell development

retina development in camera-type eye

Tight junction

CfaAffx.28443.1.S1_s_at JAK1 Janus kinase 1 (a protein tyrosine kinase) 5   PMRNA28343 Cfa.15782  

non-membrane spanning protein tyrosine kinase activity

Janus kinase activity

receptor binding

ATP binding

cytoplasm

apoptosis

cell motility

enzyme linked receptor protein signaling pathway

tyrosine phosphorylation of STAT protein

STAT protein nuclear translocation

mesoderm development

negative regulation of cell proliferation

membrane

peptidyl-tyrosine phosphorylation

cytokine and chemokine mediated signaling pathway

myeloid cell differentiation

SH2 domain binding

intracellular part

membrane raft

positive regulation of transcription from RNA polymerase II promoter

positive regulation of JAK-STAT cascade

Jak-STAT signaling pathway

Adipocytokine signaling pathway

-0.721
CfaAffx.28915.1.S1_s_at DAB1 disabled homolog 1 (Drosophila) 5   PMRNA28815    

neuron migration

phospholipid binding

receptor-mediated endocytosis

negative regulation of cell adhesion

Notch signaling pathway

protein kinase cascade

small GTPase mediated signal transduction

behavior

embryonic development ending in birth or egg hatching

cerebellum structural organization

cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration

radial glia guided migration of Purkinje cell

SH2 domain binding

positive regulation of protein kinase activity

secretion

perinuclear region of cytoplasm

positive regulation of biological process

  -0.703
CfaAffx.28978.1.S1_at SSH2 slingshot homolog 2 (Drosophila) 9   PMRNA28878 Cfa.42280  

inactivation of MAPK activity

cell morphogenesis

actin binding

non-membrane spanning protein tyrosine phosphatase activity

nucleus

cytoplasm

plasma membrane

protein amino acid dephosphorylation

response to oxidative stress

nervous system development

protein tyrosine/threonine phosphatase activity

MAP kinase tyrosine/serine/threonine phosphatase activity

actin cytoskeleton organization and biogenesis

mitogen-activated protein kinase binding

regulation of cellular component organization and biogenesis

Regulation of actin cytoskeleton

-0.703
CfaAffx.2952.1.S1_at NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1   PMRNA2852 Cfa.20560  

vasculogenesis

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

receptor activity

cytosol

integral to plasma membrane

protein amino acid phosphorylation

transmembrane receptor protein tyrosine kinase signaling pathway

feeding behavior

glutamate secretion

regulation of metabolic process

B cell differentiation

mechanoreceptor differentiation

neurotrophin binding

terminal button

retinal rod cell development

positive regulation of axon extension involved in regeneration

MAPK signaling pathway

-0.694
CfaAffx.29915.1.S1_at LCN6 lipocalin 6 9   PMRNA29815    

extracellular region

lipid biosynthetic process

intracellular membrane-bounded organelle

cytoplasmic part

regulation of circadian sleep/wake cycle, sleep

 
CfaAffx.30326.1.S1_at LOC489654 similar to Protein C16orf7 homolog (5-day ovary-specific transcript 1 protein) 5   PMRNA30226    

transporter activity

ATP synthesis coupled proton transport

GTPase regulator activity

intracellular membrane-bounded organelle

cytoplasmic part

 
CfaAffx.30365.1.S1_s_at CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 6   PMRNA30265 Cfa.25855  

reproduction

gastrulation with mouth forming second

neural tube closure

G-protein coupled receptor activity

receptor signaling protein activity

calcium ion binding

extracellular space

cytoplasm

integral to plasma membrane

segment polarity determination

axon guidance

axonal fasciculation

imaginal disc growth

imaginal disc-derived wing morphogenesis

locomotory behavior

integral to membrane

Wnt receptor signaling pathway

mushroom body development

calcium-dependent cell-cell adhesion

dendrite development

facial nucleus development

neural plate anterioposterior pattern formation

regulation of Wnt receptor signaling pathway

regulation of gene-specific transcription

establishment of ommatidial polarity

cell migration involved in gastrulation

establishment of polarity of embryonic epithelium

inner ear morphogenesis

apical protein localization

negative regulation of growth

regulation of neurotransmitter secretion

protein dimerization activity

R3/R4 cell differentiation

R3/R4 development

dendrite morphogenesis

  -0.721
CfaAffx.3054.1.S1_at LOC484150 similar to RIKEN cDNA 5133401N09 1   PMRNA2954 Cfa.24903  

kinase activity

  -0.679
CfaAffx.30766.1.S1_at PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 9   PMRNA30666    

glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex

dolichyl-phosphate beta-D-mannosyltransferase activity

protein binding

endoplasmic reticulum membrane

GPI anchor biosynthetic process

1-phosphatidylinositol-4-phosphate 5-kinase activity

protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

mannosyltransferase complex

protein amino acid O-linked mannosylation

cell projection

  -0.685
CfaAffx.30927.1.S1_at MARVELD3 MARVEL domain containing 3 5   PMRNA30827 Cfa.43179  

membrane

 
CfaAffx.4040.1.S1_s_at KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 13 -50374956 PMRNA3940 Cfa.24332 2

ovarian follicle development

patterning of blood vessels

vasculogenesis

positive regulation of mesenchymal cell proliferation

protein serine/threonine kinase activity

vascular endothelial growth factor receptor activity

ATP binding

extracellular space

integral to plasma membrane

protein amino acid phosphorylation

female pregnancy

regulation of heart contraction

cell migration

growth factor binding

hemopoiesis

thyroid gland development

embryonic heart tube development

identical protein binding

surfactant homeostasis

cell fate commitment

endothelial cell differentiation

vascular endothelial growth factor receptor signaling pathway

alveolus development

cell maturation

positive regulation of epithelial cell proliferation

calcium ion homeostasis

Cytokine-cytokine receptor interaction

VEGF signaling pathway

Focal adhesion

CfaAffx.4189.1.S1_at S1PR3 sphingosine-1-phosphate receptor 3 1   PMRNA4089    

angiogenesis

lysosphingolipid and lysophosphatidic acid receptor activity

ATP binding

integral to plasma membrane

hydrogen transport

inflammatory response

G-protein signaling, adenylate cyclase inhibiting pathway

elevation of cytosolic calcium ion concentration

brain development

positive regulation of cell proliferation

lipid binding

hydrogen-exporting ATPase activity, phosphorylative mechanism

regulation of cell adhesion

Neuroactive ligand-receptor interaction

CfaAffx.4406.1.S1_s_at PAX5 paired box 5 11   PMRNA4306    

negative regulation of transcription from RNA polymerase II promoter

ureteric bud development

cell fate specification

cell fate determination

transcription factor activity

thyroid-stimulating hormone receptor activity

protein binding

transcription factor complex

humoral immune response

axonogenesis

peripheral nervous system development

visual perception

embryonic pattern specification

transcription activator activity

transcription repressor activity

cerebellum formation

thyroid gland development

midbrain development

midbrain-hindbrain boundary development

camera-type eye development

otic placode formation

positive regulation of transcription from RNA polymerase II promoter

pronephros development

negative regulation of histone H3-K9 methylation

  -0.697
CfaAffx.4658.1.S1_s_at COL15A1 collagen, type XV, alpha 1 11   PMRNA4558 Cfa.37504  

extracellular matrix structural constituent

binding

collagen type XV

basement membrane

extracellular space

cell adhesion

organ morphogenesis

extracellular matrix organization and biogenesis

regulation of cell proliferation

cell development

positive regulation of cellular process

localization

 
CfaAffx.5646.1.S1_s_at LOC475501 similar to H2A histone family, member V isoform 5 16   PMRNA5546 Cfa.46848  

nucleosome

Barr body

nematode larval development

DNA binding

polytene chromosome

lipid particle

nucleosome assembly

locomotory behavior

embryonic development ending in birth or egg hatching

regulation of flower development

positive regulation of growth rate

post-embryonic body morphogenesis

  -0.779
CfaAffx.5829.1.S1_at BMP10 bone morphogenetic protein 10 10   PMRNA5729 Cfa.21136  

embryonic axis specification

skeletal development

osteoblast differentiation

cell fate specification

cell fate determination

compound eye morphogenesis

epithelial to mesenchymal transition

morphogenesis of an epithelium

signal transducer activity

extracellular space

intracellular

transmembrane receptor protein serine/threonine kinase signaling pathway

cell-cell signaling

germ cell development

chorion-containing eggshell formation

maternal determination of dorsal/ventral axis, oocyte, soma encoded

dorsal closure

sensory organ development

open tracheal system development

hindgut morphogenesis

imaginal disc growth

anterior/posterior pattern formation, imaginal disc

proximal/distal pattern formation, imaginal disc

imaginal disc-derived wing vein specification

imaginal disc-derived wing morphogenesis

mesoderm development

pericardial cell differentiation

imaginal disc-derived wing vein morphogenesis

determination of bilateral symmetry

anterior/posterior axis specification

dorsal/ventral axis specification

cardioblast differentiation

specific transcriptional repressor activity

stem cell division

stem cell maintenance

negative regulation of cell growth

negative regulation of cell migration

germ-line stem cell maintenance

negative regulation of gene-specific transcription

receptor serine/threonine kinase binding

cardiac cell differentiation

regulation of tube diameter, open tracheal system

eye-antennal disc development

genital disc development

labial disc development

wing disc pattern formation

genital disc anterior/posterior pattern formation

genital disc sexually dimorphic development

cell migration involved in gastrulation

germ-line stem cell division

regulation of cell proliferation

regulation of imaginal disc growth

positive regulation of cell differentiation

negative regulation of cell cycle

regulation of organ growth

dorsal appendage formation

lymph gland development

ectodermal gut morphogenesis

gland development

branching morphogenesis of a tube

cardiac muscle cell proliferation

 
CfaAffx.6253.1.S1_at NCDN neurochondrin 15   PMRNA6153 Cfa.17950      
CfaAffx.688.1.S1_at LOC491531 similar to Olfactory receptor 4C6 18   PMRNA588    

olfactory receptor activity

G-protein coupled receptor protein signaling pathway

sensory perception of smell

integral to membrane

Olfactory transduction

-0.682
CfaAffx.8011.1.S1_at ACCN3 amiloride-sensitive cation channel 3 16   PMRNA7911    

response to acid

protein binding

integral to plasma membrane

sodium ion transport

signal transduction

synaptic transmission

central nervous system development

peripheral nervous system development

phototransduction

sensory perception of sound

memory

associative learning

response to pH

response to heat

monovalent inorganic cation transmembrane transporter activity

amiloride-sensitive sodium channel activity

synaptosome

cell soma

negative regulation of apoptosis

dendritic spine

dendritic shaft

synapse

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus involved in sensory perception of pain

detection of chemical stimulus involved in sensory perception of pain

 

154 Genes