Glesne_etal2005_MRSLS_Table_S2
Function Code Annotation Category
AA-MET Amino Acid Metabolism
AF/GC Angiogenic Factors / Guidance Cues
CA Cell Adhesion
cDNA Unknown cDNA
CFD/M Cell Fate / Determination / Morphogenesis
CSO Cytoskeletal Reorganization
DEF Anti-Oxidant Defense System / Detoxification / Defense
ECM Extracellular Matrix proteins
H/TF Homeobox / Transcription Factor
HYP Hypothetical proteins
ICT/S Intracellular Trafficking / Secretion / Vesicular Transport
L-MET Lipid Metabolism
M/CT Motility / Chemotaxis
MET Cellular Metabolism
MHC Major Histocompatibility Complex
MT Membrane Transporters
P/MMP Protease;Matrix Metalloprotease
PDP Protein Degradation Pathway
PP Protein Processing
R Receptors
RP RNA processing/binding; splicing factor
ST Signal Transduction
UF Unknown Function
MRSLs that begin to increase at 30 minutes
Affymetrix HG U133 Probe ID Function Code GenBank Accession Gene Symbol Gene Title
215682_at AA-MET AB051440.1 PRODH Proline Dehydrogenase (oxidase) 1
204836_at AA-MET NM_000170.1 GLDC Glycine Dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P)
201645_at CA NM_002160.1 HXB Hexabrachion (tenascin C)
202328_s_at CA NM_000296.1 PKD1 Polycystic Kidney Disease 1
205567_at CA NM_003654.1 CHST1 Carbohydrate (keratan sulfate Gal-6) Sulfotransferase 1
202790_at CA NM_001307.1 CLDN7 Claudin 7
235546_at CFD/M AI739289 SPINT1/HAI Serine Protease Inhibitor, Kunitz type 1
212488_at CFD/M AI983428 COL5A1 Collagen, type V, alpha 1
219019_at CFD/M NM_018494.1 LRDD/PIDD Leucine-rich Repeats and Death Domain Containing Protein
211607_x_at CFD/M U48722.1 truncated form of EGFR Epidermal Growth Factor Receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
214940_s_at CFD/M AB018275.1 EST1A Ever shorter telomeres1A
232764_at CFD/M BF509102 CCNB2 Cyclin B2
228535_at CFD/M AI796010 RAD1 RAD1 DNA Repair Protein
223525_at CFD/M AB036931.1 DLL4 Delta-like 4 (Drosophila)
228081_at CFD/M BF061444 CCNG2 Cyclin G2
232883_at CSO H88923 SOS1 Son of Sevenless Homolog 1 (Drosophila)
218980_at CSO NM_025135.1 FHOD3/FHOS2 Formin homology 2 domain containing 3
217849_s_at CSO NM_006035.1 CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
202023_at CSO NM_004428.1 EFNA1 Ephrin-A1
213792_s_at DEF AA485908 INSR Insulin Receptor
203814_s_at DEF NM_000904.1 NQO2/NMOR2 NAD(P)H dehydrogenase, quinone 2
231628_s_at DEF AW262311 SERPINB6/PI-6/SPI3 Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6
236225_at DEF AI697028 FLJ90165 Hypothetical Protein FLJ90165
204418_x_at DEF NM_000848.1 GSTM2 Glutathione S-transferase M2(muscle)
203417_at ECM NM_017459.1 MFAP2 Microfibrillar-associated protein 2
218860_at ECM NM_024078.1 MGC3162 Hypothetical Protein MGC3162
235087_at H/TF BG335934 UNKL Unkempt (Drosophila)-like
210022_at H/TF BC004952.1 POLYCOMB/NSPC1/RNF3A-2 Polycomb Group Ring finger 1
223687_s_at H/TF AA723810 LY6K/CO16/HSJ001348 Lymphocyte Antigen 6 Complex, locus K
241112_at H/TF H46217 ENST00000276823 ENST00000276823
231931_at H/TF AL355710.1 PRDM15/ZNF298 PR domain containing 15
211597_s_at H/TF AB059408.1 HOP/Cameo/Toto Homeodomain-only protein
220911_s_at H/TF NM_025081.1 KIAA1305 KIAA1305
225667_s_at H/TF AI601101 NSE1 non-SMC element 1 homolog (S. cerevisiae)
205267_at H/TF NM_006235.1 POU2AF1/OBF1/Bob1 POUdomain,class2,associatingfactor1
230889_at H/TF AW242668 SALL3 Spalt-like gene3
228425_at H/TF BF056746 PAX8 Paired Box Gene 8
236847_at HYP AI650509 C19ORF18 Hypothetical Protein MGC41906
239854_at HYP AA953200 ENSG00000130487 ENSG00000130487
212316_at ICT/S AB020713.1 NUP210/POM210 Nuclear Pore Membrane Glycoprotein 210
224668_at ICT/S AL021578 SYS1/C20orf35/HSMNP1  Protein SYS1 homolog
223973_at ICT/S AB058893.1 PGSF1B Pituitary Gland Specific Factor 1b
234071_at ICT/S AU147969 DEPDC6 DEP domain containing 6
225962_at ICT/S AL390144.1 NIN283/ZNRF1 Nerve Injury Gene 283/zinc and ring finger 1
234717_at ICT/S Y13187 DMD DMD gene, intron 11/Dystrophin
209193_at ICT/S M24779.1 PIM1 Proto-oncogene serine/threonine-protein kinase
239998_at ICT/S AI990484 C10orf53 Chromosome 10 Open Reading Frame 53
221845_s_at ICT/S AI655698 SKD3 Suppressor of Potassium Transport Defect 3
242816_at ICT/S AI339489 GNAS Guaninenucleotide-binding protein G(S), alpha subunit
202452_at ICT/S NM_006336.1 C9orf60 ZYG homolog
203549_s_at L-MET NM_000237.1 LPL Lipoprotein Lipase
244266_at L-MET AI583235 AKR1C2/DD2/HAKRD Aldo-Keto Reductase Family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
240024_at L-MET AI571796 SEC14L2 SEC14-like 2 (S. cerevisiae)
213343_s_at L-MET AL041124 PP1665/GDPD5 Hypothetical Protein PP1665 / Glycerophosphodiester Phosphodiesterase Domain containing 5
238279_x_at L-MET BF062155 COL4A3BP/CERT/StARD11 Collagen, Type IV, alpha-3 Binding Protein
239104_at M/CT AW274408 CENTD1/ARAP2/PARX Centaurin, delta 1
229642_at M/CT AW139757 ARHGEF7/COOL-1/p85 Rho guanine nucleotide exchange factor (GEF) 7
231591_at MET AV659897 BHMT Betaine-Homocysteine Methyltransferase
231487_at MET AW269746 COX8-3 Cytochrome C Oxidase Subunit VIII isoform 3
242716_at MT AI804642 SLC30A1/ZnT1 Solute Carrier Family 30 (zinc transporter), member 1
230610_at MT AW008915 MCLC-1 Mid-1-related chloride channel 1
209847_at MT U07969.1 CDH17 Cadherin 17, LI cadherin (liver-intestine)
222677_x_at PDP NM_017900.1 AKIP/AIP Aurora-A kinase interacting protein
243152_at PDP AW291930 COP9 Signalosome complex subunit 8
231044_at PP AI652292 POMGNT1 Protein O-mannose beta-1,2-N-acetylglucosaminyltransferase
230497_at RP BE503640 BRUNOL5 Bruno-like 5, RNA binding protein (Drosophila)
232853_at RP AW518747 MEP50 Methylosome Protein 50
229303_at RP AI018793 SF3B1/SAP155 Splicing factor 3b, subunit 1, 155kDa
205048_s_at ST NM_003832.1 PSPHL/CO9 Phosphoserine Phosphatase-like
226055_at ST AK000689.1 ARRDC2 Arrestin Domain Containing 2
223434_at ST AL136680.1 GBP3/atlastin/SPG3A Guanylate Binding Protein 3
221215_s_at ST NM_020639.1 RIP4/ANKRD3//DIK Receptor-interacting Serine-Threonine kinase 4
MRSLs that begin to increase at 1 hour
Affymetrix HG U133 Probe ID Function Code GenBank Accession Gene Symbol Gene Title
232226_at AF/GC AW118214 NGL-1 Netrin-G1 ligand
213004_at AF/GC AF007150.1 ANGPTL2/ARP2 Angiopoietin-like 2
210132_at AF/GC AW189015 EFNA3/LERK3/EHK1 ligand Ephrin-A3
211587_x_at AF/GC M37981.1 CHRNA3 Cholinergic receptor, nicotinic, alpha polypeptide 3
202037_s_at AF/GC NM_003012.2 SFRP1/FRZA Secreted frizzled-related protein 1
227240_at AF/GC AV703769 NGEF/Ephexin Neuronal guanine nucleotide exchange factor
209897_s_at AF/GC AF055585.1 SLIT2 Slit homolog 2
216705_s_at AF/GC X02189 ADA Adenosine deaminase
202668_at AF/GC BF001670 EFNB2 Ephrin-B2
206148_at AF/GC NM_002183.1 IL3RA/CD123 Interleukin 3 receptor, alpha (low affinity)
231361_at CA AI912122 NLGN1 Neuroligin 1
203988_s_at CA NM_004480.1 FUT8 Fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
40687_at CA M96789 GJA4 Gap Junction Protein, alpha 4, 37kDa (connexin 37)
203779_s_at CA NM_005797.1 EVA1/MPZL2 Epithelial V-like antigen 1
234331_s_at cDNA AK025063.1 NSE1 Non-SMC (Structural maintenance of chromosomes) element 1 protein
226034_at CF/D BE222344 DUSP4/MKP-2 Dual specificity phosphatase 4
210592_s_at CFD/M M55580.1 SAT/SSAT Spermidine/spermine N1-acetyltransferase
214315_x_at CFD/M/ICT/S AI348935 CALR Calreticulin
233795_at CSO AL133658.1 ODF3/SHIPPO-1 Outer dense fiber of sperm tails 3
218678_at CSO NM_024609.1 NES Nestin
205547_s_at CSO NM_003186.2 TAGLN/SM22/WS3-10 Transgelin
223130_s_at CSO AF212221.1 MYLIP/MIR Myosin Regulatory Light Chain Interacting Protein
213711_at CSO NM_002281.1 KRTHB1 Keratin, hair, basic, 1
201650_at CSO NM_002276.1 KRT19 Keratin 19
202554_s_at DEF AL527430 GSTM3 Glutathione S-transferase M3 (brain)
204550_x_at DEF NM_000561.1 GSTM1 Glutathione S-transferase M1
228261_at ECM BE045549 MIB2/ZZZ5/skeletrophin Mindbomb homolog 2 (Drosophila)/zinc finger, ZZ type with ankyrin repeat domain 1
226991_at H/TF AA489681 NFATC2/NFAT1 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
238476_at H/TF AA481560 LOC153222 Adult Retinal protein
244288_s_at H/TF BF433916 SIX3 Sine oculis homeobox homolog 3 (Drosophila)
213059_at H/TF AF055009.1 CREB3L1/OASIS cAMP responsive element binding protein 3-like 1
211736_at H/TF BC005914.1 Sp2 Sp2 transcription factor
244304_at H/TF AW129650 MGC42174 Hypothetical protein MGC42174
220618_s_at H/TF NM_017984.1 ZCWPW1 Zinc finger, CW type with PWWP domain 1
240150_at H/TF BE467740 RP42/SCRO RP42 homolog
203505_at L-MET AF285167.1 ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
205749_at L-MET NM_000499.2 CYP1A1 Cytochrome P450, family 1, subfamily A, polypeptide 1
203756_at M/CT NM_014786.1 ARHGEF17/p164 Rho GEF Rho guanine nucleotide exchange factor (GEF) 17
217028_at M/CT AJ224869 CXCR4  Chemokine (C-X-C motif) receptor 4
239744_at M/CT AW151660 RGS3 Regulator of G-protein signaling 3
201137_s_at MHC NM_002121.1 HLA-DPB1  Major histocompatibility complex, class II, DP beta 1
203435_s_at P/MMP NM_007287.1 MME Membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
240265_at ST AI214464 T3JAM TRAF3-interacting Jun N-terminal kinase (JNK)-activating modulator
221563_at ST N36770 DUSP10/MKP5 Dual specificity phosphatase 10
206389_s_at ST NM_000921.1 PDE3A Phosphodiesterase 3A, cGMP-inhibited
MRSLs that begin to increase at 2 hours
Affymetrix HG U133 Probe ID Function Code GenBank Accession Gene Symbol Gene Title
204279_at PDP NM_002800.1 PSMB9/LMP2/RING12 Proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2)
226834_at CA BG112263 ASAM Adipocyte-Specific Adhesion Molecule
221731_x_at ECM/AF/GC J02814.1 CSPG2/versican Chondroitin Sulfate Proteoglycan 2 (versican)
204681_s_at ST/M/CT NM_012294.1 RAPGEF5/MR-GEF/GFR  Rap guanine nucleotide exchange factor (GEF) 5
237001_at ICT/S AW137997 T1 Tularik gene 1
203859_s_at M/CT NM_002579.1 PALM Paralemmin
236088_at AF/GC AV723308 NTNG1  Netrin G1
204567_s_at L-MET NM_004915.2 ABCG1  ATP-binding cassette, sub-family G (WHITE), member 1
202295_s_at PDP NM_004390.1 CTSH Cathepsin H
218211_s_at ICT/S NM_024101.1 MLPH/SLac2a Melanophilin
231015_at H/TF/L-MET AW014734 KLF15 Kruppel-like factor 15
221560_at CSO AB049127.1 MARK4/MARKL1 MAP/microtubule affinity-regulating kinase 4
220685_at UF NM_017848.1 CXorf17  BJ-HCC-21 tumor antigen
216944_s_at M/CT U23850.1 ITPR1 Inositol 1,4,5-triphosphate receptor, type 1
215111_s_at CFD/M AK027071.1 TGFB1I4/TSC-22 Transforming Growth Factor beta 1 induced transcript 4
201506_at CA NM_000358.1 TGFBI Transforming Growth Factor, beta-induced, 68kDa
235746_s_at ST BE048919 PLA2R1 Phospholipase A2 receptor 1, 180kDa
36564_at PDP W27419 IBRDC3 IBR domain containing 3
209723_at DEF BC002538.1 SERPINB9/CAP3 Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9
212356_at CA AI075450 KIAA0323/C14orf124/HCDI protein KIAA0323 protein
204817_at CC/P/MMP NM_012291.1 ESPL1  Extra spindle poles like 1 (S. cerevisiae)
211959_at CFD/M L27560.1 IGFBP5 Insulin-like growth factor binding protein 5
204955_at CA NM_006307.1 SRPX Sushi-repeat-containing protein, X-linked
203140_at H/TF NM_001706.1 BCL6/LAZ-3 B-cell CLL/lymphoma 6 (zinc finger protein 51)
229404_at H/TF AI086614 TWIST2/DERMO1 Twist homolog 2 (Drosophila)
209765_at P/MMP Y13786.2 ADAM19/MADDAM A disintegrin and metalloproteinase domain 19 (meltrin beta)
232505_at ICT/S AU147214 DCTN2 Dynactin 2 (p50)
213844_at H/TF NM_019102.1 HOXA5 Homeo box A5
234740_at CFD/M AK024886.1 CDC14B Dual specificity protein phosphatase CDC14B (CDC14 cell division cycle 14 homolog B)
224409_s_at ST AF348077.1 SSTK/FKSG82 Serine/Threonine protein kinase SSTK
201286_at CA/CSO Z48199 SDC1  Syndecan 1
33304_at CFD/M/RNAP U88964 ISG20/HEM45 Interferon stimulated gene 20kDa
241710_at ICT/S AI436290 PLEKHH2 Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
209081_s_at CA NM_030582.1 COL18A1 Collagen, type XVIII, alpha 1
232122_s_at M/CT AK022666.1 VEPH1 Ventricular Zone Expressed PH domain homolog 1
201354_s_at H/TF NM_013449.1 BAZ2A  Bromodomain adjacent to zinc finger domain, 2A
202756_s_at CA NM_002081.1 GPC1  Glypican 1
218451_at CA NM_022842.1 CDCP1/SIMA135 CUB domain containing protein 1
241748_x_at UF AI954654 DGCR14/DGSI  DiGeorge syndrome critical region gene 14
234725_s_at AF/GC AK026133.1 SEMA4B/SEMAC Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
230963_at H/TF anti-sense BF592111 EMX2OS Empty spiracles homolog 2 (Drosophila) opposite strand
208690_s_at ICT/S BC000915.1 PDLIM1/CLIM1 PDZ and LIM domain 1 (elfin)
210032_s_at M/CT AI651156 SPAG6 Sperm associated antigen 6
202743_at ST BE622627 PIK3R3 Phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)
232315_at H/TF AU149712 ZNF528 Zinc finger protein 528
203543_s_at H/TF NM_001206.1 KLF9/BTEB1  Kruppel-like factor 9/basic transcription element binding protein 1
203789_s_at AF/GC NM_006379.1 SEMA3C/SEMAE Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
203723_at ST NM_002221.1 ITPKB Inositol 1,4,5-trisphosphate 3-kinase B
206074_s_at H/TF NM_002131.1 HMGA1 High mobility group AT-hook 1
210150_s_at ECM BC003355.1 LAMA5  Laminin, alpha 5
242519_at CA/DEF BF432331 SEPP1 Selenoprotein P precursor (SeP).
212463_at DEF BE379006 CD59 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
224540_at ICT/S AF238867.1 LACRT  Lacritin
204990_s_at CA NM_000213.1 ITGB4 Integrin, beta 4
216986_s_at H/TF D78261.1 IRF4  Interferon regulatory factor 4
202391_at ICT/S/M/CT NM_006317.1 BASP1  Brain abundant, membrane attached signal protein 1
206467_x_at DEF NM_003823.1 TNFRSF6B  Tumor necrosis factor receptor superfamily, member 6b, decoy
213421_x_at P/MMP AW007273 PRSS3  Protease, serine, 3 (mesotrypsin)
207375_s_at DEF NM_002189.1 IL15RA  Interleukin 15 receptor, alpha
230815_at ICT/S AI684760 KIF27A Kinesin family member 27
207760_s_at H/TF NM_006312.1 NCOR2/SMRT/TRAC Nuclear receptor co-repressor 2
1007_s_at CA U48705 DDR1/NTRK4/NEP Discoidin domain receptor family, member 1
222799_at ST AK001606.1 HSPC049/NM_014149 HSPC049 protein
46665_at M/CT AI949392 SEMA4C/SEMAF Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
MRSLs that begin to increase at 4 hours
Affymetrix HG U133 Probe ID Function Code GenBank Accession Gene Symbol Gene Title
230836_at CA AI422986 ST8SIA4/PST1  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
225368_at CFD/M BF218115 HIPK2  Homeodomain interacting protein kinase 2
207643_s_at CFD/M NM_001065.1 TNFRSF1A  Tumor necrosis factor receptor superfamily, member 1A
212495_at H/TF AW237172 JMJD2B  Jumonji domain containing 2B
223589_at H/TF BC000130.1 ZNF416/NM_017879 Zinc finger protein 416/Hypothetical protein FLJ20557
203278_s_at H/TF NM_016621.1 PHF21A/BHC80  PHD finger protein 21A
235052_at H/TF AV758821 FLJ38451/NM_175872  FLJ38451 protein
204431_at H/TF NM_003260.1 TLE2/ESG2  Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
213230_at H/TF AI422335 HUMPPA Paraneoplastic antigen
227287_at H/TF AW027167 CITED2/MRG1 Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG1 protein) (P35srj).
213625_at H/TF AW190088 ZNF307  Zinc finger protein 307
202815_s_at H/TF/CFD/M NM_006460.1 HIS1 Hexamethylene bisacetamide-inducible protein
222557_at ICT/S AL353715 STMN3  Stathmin-like 3
236718_at ICT/S AI278445 MYO10 Myosin X
202315_s_at M/CT NM_004327.2 BCR  Breakpoint Cluster Region
225649_s_at M/CT AA001414 STK35/Clik1 Serine/Threonine kinase 35
226673_at M/CT AW665063 SH2D3C  SH2 domain containing 3C
225685_at M/CT AI801777 CDC42EP3/CEP3/BORG2 CDC42 effector protein (Rho GTPase binding) 3
224469_s_at M/CT BC006173.1 C14orf151/MGC13251  Chromosome 14 open reading frame 151
203962_s_at M/CT NM_006393.1 NEBL  Nebulette
236163_at M/CT AW136983 LIX1/C5orf11  Lix1 homolog (mouse)
202934_at MET AI761561 HK2 Hexokinase 2
202499_s_at MT NM_006931.1 SLC2A3/GLUT3 Solute carrier family 2 (facilitated glucose transporter), member 3
228836_at MT AI344200 FLJ40217/NM_201520 Hypothetical protein FLJ40217
226506_at P/MMP AI742570 FLJ13710/NM_024817 Hypothetical protein FLJ13710
219282_s_at R NM_015930.1 TRPV2/VRL-1  Transient receptor potential cation channel, subfamily V, member 2
31637_s_at R/L-MET X72631 THRA/NR1A1 Thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
223538_at RP AF073518.1 SERF1A  Small EDRK-rich factor 1A (telomeric)
227512_at SF AW248508 LOC92312/FLJ43493/AK125482 Hypothetical protein LOC92312
244608_at ST AA412686 WWTR1/TAZ-1 WW domain containing transcription regulator 1/transcriptional co-activator with PDZ-binding motif
223199_at ST AA404592 MKNK2 MAP kinase interacting serine/threonine kinase 2
225510_at UF BG033561 NS5ATP13TP2 NS5ATP13TP2 protein
221565_s_at UF BC000039.1 FAM26B  Family with sequence similarity 26, member B
238465_at UF AI265933 MGC33648 Hypothetical protein MGC33648
MRSLs that begin to increase at 8 hours
Affymetrix HG U133 Probe ID Function Code GenBank Accession Gene Symbol Gene Title
204295_at MET NM_003172.1 SURF1  Surfeit 1
203000_at ICT/S BF967657 STMN2  Stathmin-like 2