This Perspective refers to the following articles:
Chemopreventive Effect of Kava on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone plus Benzoapyrene�Induced Lung Tumorigenesis in A/J Mice
Thomas E. Johnson, Fekadu Kassie, M. Gerard O'Sullivan, Mesfin Negia, Timothy E. Hanson, Pramod Upadhyaya, Peter P. Ruvolo, Stephen S. Hecht and Chengguo Xing

Effects of the Kava Chalcone Flavokawain A Differ in Bladder Cancer Cells with Wild-type versus Mutant p53
Yaxiong Tang, Anne R. Simoneau, Jun Xie, Babbak Shahandeh and Xiaolin Zi

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