This Perspective refers to the following articles:

Intratumoral Epiregulin Is a Marker of Advanced Disease in Non�Small Cell Lung Cancer Patients and Confers Invasive Properties on EGFR-Mutant Cells
Jie Zhang, Kentaro Iwanaga, Kuicheon C. Choi, Marie Wislez, Maria Gabriela Raso, Wei Wei, Ignacio I. Wistuba, and Jonathan M. Kurie Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas
Ximing Tang, Marileila Varella-Garcia, Ana C. Xavier, Erminia Massarelli, Natalie Ozburn, Cesar Moran, and Ignacio I. Wistuba

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